Hyaluronic acid is one of the main components of connective tissues together with collagen and elastin fibres. It is a polysaccharide naturally produced by the body in order to protect the tissues and keep them hydrated. It is possible to apply ACTI-BONE® directly on the surgical site, or use it in combination with RE-BONE® bone substitute to obtain the so-called “sticky bone” or with SHELTER® FAST or SHELTER® SLOW pericardium membranes to enhance their chemotactic capacity.