Shelter Membrane 0.4mm&0.8mm

SHELTER is a pericardium membrane of bovine origin and, thanks to the innovative Pericross decellularization system, the three-dimensional structure of collagen is maintained.
The multidirectional composition of the pericardial collagen fibers allows for greater stability and protection to the graft site.
At UBGEN we have developed two types of membranes:
• SHELTER Fast, a membrane with a fast resorption time (4-5 weeks) thanks to the particular broad-textured collagen structure;
• SHELTER Slow, a membrane with a slower resorption time (3-6 months) due to a modified three-dimensional structure of collagen fibres, that are more resistant because of intensified bonds.
SHELTER Fast and SHELTER Slow are occlusive to the passage of cells. They are designed to promote osteoblastic and periodontal ligament cells proliferation, protecting the site from soft tissue colonization; stable and resistant to traction they are easy and manageable in positioning.
 Why to choose SHELTER
1. Optimal clinical handling: Shelter adapts perfectly to the contours of the defect, does not stick to gloves or instruments;
2. The multilayer structure makes it elastic and flexible;
3. It can be used on both sides indifferently;
4. It is particularly resistant to traction: it accepts a wide range of sutures and fastening systems;
5. Supports neoangiogenesis;
6. It has chemotactic capacity, the tissues heal quickly in case of post-op dehiscence;
7. It has controlled resorption times.

Re-Bone Block 10 x 10 x 20mm

RE-BONE® WHY CHOOSE IT?

Because it works.
• UBGEN® is the only certified Italian company that processes bovine material at low temperatures. Most of the commercially available biomaterials do not use raw material of bovine origin, or exploit bovine bone treated at high temperatures.
This means that the resorption index is significantly lower and that the bone graft remains in the oral cavity even after many years.
At UBGEN® we exploit the winning characteristics of the bone substitute of bovine origin, treated at low temperature through our unique Thermagen production process. The bone substitute thus produced has been shown to facilitate in situ volumetric stability, thanks to the superficial cracking of the granules technology. Moreover, this low temperature cleaning process prevents ceramization, while keeping the bovine bone matrix perfectly resorbable and biocompatible.
RE-BONE® is completely reabsorbed in 6-8 months. Its safety is ensured by the choice of raw material in compliance with the standards required in the reference protocol.
The first bone graft of bovine origin processed at low temperature
• ▷ Fully resorbable
▷ Processed at low temperatures thanks to the Thermagen production process
▷ Produced by an entirely Italian supply chain
▷ MCE marked as a product compliant with Directive 93/42 EEC (CE 0373)

• Compared to the presence on the market of bone substitutes of bovine origin treated at high temperatures or produced with raw materials from other sources (porcine, equine, synthetic), at UBGEN® we enhance the winning characteristics of the bovine bone substitute with the innovative Thermagen production process at low temperatures. Thanks to this protocol, we are able to avoid the so-called “ceramization” of the bone substitute, thus ensuring its total resorption and giving it high biocompatibility as well as adequate macro/microporosity.
The decellularization process of the Thermagen raw material was developed by a team of internal and external bioengineering experts and subsequently proven by tests performed by authoritative University Departments.

Together with the Thermagen production process, it is the choice of the raw material that makes the difference. At UBGEN® we are aware of the details of each step of the production chain: from the wholesomeness of the land used for grazing, to the natural cultivation used for the production of forage, to the healthful state of the facilities that welcome the animals themselves .
If animals live and grow well, in a healthy environment, that is respected in its territorial characteristics, the derived products intrinsically meet the health and safety requirements.
RE-BONE® is a bone substitute that is very similar to human bone tissue. Therefore, it is able to create an environment favorable to chemotaxis, osteoblast proliferation and neoangiogenesis thanks to the maintenance of the native three-dimensional structure of the extracellular matrix.
Biocompatibility of RE-BONE® bone substitute

Re-Bone 0.5gr&1gr&2gr

RE-BONE® is a CE certified bone substitute of bovine origin produced in Italy, designed to promote tissue regeneration in bone and reconstructive surgery. It is produced by processing the epiphyses of bovine femurs at low temperature (Thermagen® process), thus avoiding the issues derived from high temperature processing. The bovines are carefully selected by ISO certified slaughterhouses that guarantee a maximum age of 24-month cattle, born, raised and bred in Italy.
 
The Thermagen® process ensures high biocompatibility, higher porosity granules, better stability, absence of ceramization with raw material, total reabsorption and the conservation of the main bone markers.

Acti-Bone bottle 5ml

Hyaluronic acid is one of the main components of connective tissues together with collagen and elastin fibres. It is a polysaccharide naturally produced by the body in order to protect the tissues and keep them hydrated. It is possible to apply ACTI-BONE® directly on the surgical site, or use it in combination with RE-BONE® bone substitute to obtain the so-called “sticky bone” or with SHELTER® FAST or SHELTER® SLOW pericardium membranes to enhance their chemotactic capacity.